Plasmapheresis Market by Product (Instruments, Disposables), Technology (Membrane Filtration, Centrifugation), Application (Therapeutic [Immunology, Neurology, Hematology], Plasma Collection), End User (Biopharma, Hospitals) - Global Forecast to 2030

The Plasmapheresis Market is projected to reach $2.55 billion by 2030, at a CAGR of 8.6% from 2023 to 2030. Plasmapheresis is the process of removal, treatment, and return/exchange of plasma from the body's circulatory system. It is performed for either therapeutic purposes or for collecting source plasma for the manufacturing of blood products.

For therapeutic purposes, this procedure is used to treat a variety of conditions, such as autoimmune diseases, blood disorders, and neurologic disorders. Plasmapheresis is carried out using an instrument that separates the plasma from the blood cells. The rising demand for source plasma and plasma exchange procedures for therapeutic purposes is driving demand for plasmapheresis systems globally.

The growth of this market is driven by the rising incidence of autoimmune diseases, increasing demand for source plasma from biopharmaceutical companies, and favorable reimbursement policies for plasmapheresis procedures. In addition, the rising demand for plasmapheresis from emerging countries is expected to provide significant growth opportunities for this market.

However, the high cost of plasmapheresis devices & procedures and the risks associated with plasmapheresis procedures are expected to hinder the growth of this market to a certain extent. In addition, factors such as the lack of awareness about plasmapheresis procedures and limited access and availability in certain regions are the major challenges to the growth of this market.

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Increasing Demand for Source Plasma from Biopharmaceutical Companies to Drive Market Growth

There is an increasing demand for source plasma from biopharmaceutical companies owing to its use in treating an expanding list of debilitating, chronic and life-threatening disorders. Plasma can be separated from the whole blood with the help of plasmapheresis procedures. The source plasma is utilized by biopharmaceutical companies to produce plasma-derived therapies using plasma-fractionation techniques and several innovative processes.

Plasma-derived therapies are helpful in treating a wide range of chronic and life-threatening diseases. For instance, immunoglobulin (IG) is used to help patients suffering from primary and secondary immunodeficiency disorders and to combat viral and bacterial infections. There is a high demand for source plasma from biopharmaceutical companies with the help of plasmapheresis procedures.

In addition, the growing incidences of various rare diseases such as hereditary angioedema, hemophilia A & B, Von Willebrand disease, primary immunodeficiency disease (PID), chronic inflammatory demyelinating polyneuropathy (CIDP), and idiopathic thrombocytopenic purpura (ITP) are also driving the demand for plasma-derived products, thereby contributing to the growth of the plasmapheresis market.

Risk Associated with Plasmapheresis Procedures to Hinder Market Growth

During the plasmapheresis procedure, some amount of blood is removed from the human body, and certain replacement fluids such as albumin, fresh frozen plasma (FFP), electrolyte solutions, purified protein products, and starches are infused in the body to maintain intravascular osmotic pressure. The procedure is usually considered safe; however, there are still several risks associated with it. Some of the risk factors associated with the plasmapheresis procedure are the risk of infection, allergic reactions, low blood pressure, internal bleeding, and electrolyte imbalance, among others.

One of the most common side effects associated with the plasmapheresis procedure is the occurrence of hypotension or lowering of blood pressure which causes faintness, blurred vision, dizziness, sweating or abdominal cramps, but these can be controlled if treated immediately.

Some patients feel numbness or tingling around the mouth or nose, owing to the effect of citrate, an anticoagulant, on the calcium level in the body. Occasionally, bleeding can occur during the plasmapheresis procedure because of anticoagulants added to the blood, and if not treated immediately can result in irregular heartbeat and cardiac arrest. The replacement fluids sometimes cause an allergic reaction, itching, and rash. It can be treated easily with intravenous medication. These side effects can hamper the repeated adoption of plasmapheresis, which restricts the growth of this market to a certain extent.

Key Findings of the Plasmapheresis Market Study:

In 2023, the Disposables Segment is Expected to Dominate the Plasmapheresis Market

Based on product, the plasmapheresis market is segmented into instruments and disposables. In 2023, the disposables segment is expected to account for the larger share of the plasmapheresis market. The disposables include consumables such as plasma separation filters and administration sets. The large market share of this segment is attributed to the rising requirement for new disposables with each increasing plasmapheresis procedure or session.

In 2023, the Centrifugation Segment is Expected to Dominate the Plasmapheresis Market

Based on technology, the plasmapheresis market is segmented into centrifugation and membrane filtration. In 2023, the centrifugation segment is expected to account for the larger share of the plasmapheresis market. The large market share of this segment is attributed to the higher adoption of centrifugation technology in donor apheresis due to its various advantages, such as cost-effectiveness in related disposables and more efficient removal of plasma.

In 2023, the Source Plasma Collection Segment is Expected to Dominate the Plasmapheresis Market

Based on application, the plasmapheresis market is segmented into source plasma collection and therapeutic plasmapheresis. In 2023, the source plasma collection segment is expected to account for the larger share of the plasmapheresis market. The large market share of this segment is attributed to the huge demand for source plasma from biopharmaceutical companies for plasma fractionation and production of plasma proteins.

In 2023, the Blood Banks & Plasma Collection Centers Segment is Expected to Dominate the Plasmapheresis Market

Based on end user, the plasmapheresis market is segmented into blood banks & plasma collection centers, hospitals & clinics, biopharmaceutical companies and other end users. In 2023, the blood banks & plasma collection centers segment is expected to account for the largest share of the plasmapheresis market. The large market share of this segment is attributed to the increasing awareness about donating plasma for plasma-derived therapies and favorable reimbursement policies for plasmapheresis procedures.

Asia-Pacific: The Fastest-growing Regional Market

Asia-Pacific is slated to record the highest CAGR in the plasmapheresis market during the forecast period. The growth of this market is driven by the rapidly growing healthcare sector, rising demand for plasma-derived products, and the growing medical tourism industry in the region.

Key Players:

The report includes a competitive landscape based on an extensive assessment of the market based on product, technology, application, end user, and geography. The report also provides insights into the geographic presence of major market players and their key growth strategies in the last three to four years. The key players profiled in the plasmapheresis market are Asahi Kasei Corporation (Japan), Terumo Corporation (Japan), Baxter International Inc. (U.S.), B. Braun Melsungen AG (Germany), SB-Kawasumi Laboratories, Inc  (Japan), Kaneka Corporation (Japan), Haemonetics Corporation (U.S.), Fresenius SE & Co. KGaA (Germany), Shanghai Dahua Medical Apparatus Co., Ltd. (China), and Infomed SA (Switzerland).

Scope of the Report:

Plasmapheresis Market, by Product

• Instruments
• Disposables

Plasmapheresis Market, by Technology

• Membrane Filtration
• Centrifugation

Plasmapheresis Market, by Application

• Source Plasma Collection
• Therapeutic Plasmapheresis
  • Immunology
  • Neurology
  • Hematology
  • Critical Care
  • Hematology-oncology
  • Rheumatology & Orthopedics
  • Other Therapeutic Applications
    (Note: Other therapeutic applications primarily include the management of respiratory diseases and wound healing.)

Plasmapheresis Market, by End User

• Blood Banks & Plasma Collection Centers
• Hospital & Clinics
• Biopharmaceutical Companies
• Other End Users
  (Note: Other end users primarily include mobile plasmapheresis centers, research institutes, and government organizations.)

Plasmapheresis Market, by Geography

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Switzerland
  • Rest of Europe (RoE)
• Asia-Pacific
  • China
  • Japan
  • India
  • Australia
  • Rest of Asia-Pacific (RoAPAC)
• Latin America
• Middle East & Africa

Key questions answered in the report: