The Mice Model Market is poised to grow at a CAGR of 6.5% from 2023 to 2030 to reach $2.48 billion by 2030. Animal models have provided significant improvement to the understanding of pathophysiology of neurodegenerative diseases. Conversely, as neurodegenerative human diseases are heterogeneous in both pathological and clinical (or behavioral) domains, animal models only recapitulate part of this complex scenario. Moreover, much attention has been paid to genetic or transgenic animal models, while most human cases of neurodegenerative diseases are sporadic, rather than familial. Therefore, there is a great challenge ahead to develop the next generation of animal models to effectively help treat and prevent neurodegenerative diseases. Thus, mice model promises the development of better treatment for the reduction in the growing neurodegenerative disorders across the globe in the near future.
Here are the top 10 companies operating in Mice Model Market
Charles River Laboratories International, Inc.
Founded in 1947 and headquartered at Wilmington, Massachusetts, U.S.; Charles River Laboratories International, Inc. provides basic research, drug discovery, safety and efficacy assessment and process manufacturing service to biotechnology, pharmaceuticals, and research organizations globally. The company operates in three reporting segments such as Research and Model Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Support (Manufacturing). Through its RMS segment, the company supplies research models to the drug development industry since 1947. The Company also provides a variety of services that are designed to assist researchers in supporting the use of research models in drug discovery and development. The company’s research model’s business is comprised of the production and sale of research models. The major part of this business is focused on the commercial production and sale of research models, principally purpose-bred rats and mice for the basic research. The company provides various types of mice research models such as outbred, inbred, spontaneous mutant, hybrid, and other genetically modified research models including knock-out models with one or more disabled genes and transgenic models.
The research model services include the maintenance and monitoring of research models, and managing research operations for government entities, academic organizations, and commercial customers. The Company currently has three service offerings in research model’s services, namely Genetically Engineered Models and Services (GEMS), Insourcing Solutions (IS), and Research Animal Diagnostic Services (RADS).
Charles River Laboratories International, Inc. has its geographic presence in North America, Europe, APAC, Israel and Brazil.
The Jackson Laboratory
Founded in 1929 and headquartered at Bar Harbor, Maine, U.S.; The Jackson Laboratory is basically involved in the mammalian genetics and human genomics research. The company also provides education to students of various ages through internships, courses, and programs. The company discovers genetic basis for preventing, treating, and curing human diseases such as cancers, stem cell research, computational biology, developmental and reproductive biology, immunology, metabolic diseases, and neurobiology. In addition, it offers mouse breeding and research services designed for mouse-based biomedical research community, such as breeding and colony management, cryopreservation and recovery, phenotyping and efficacy testing, genetic research services, and study-ready induced models.
The laboratory has its geographic presence in North America, along with 75 countries across the globe.
Laboratory Corporation of America Holdings
Founded in 1971 and headquartered at Burlington, North Carolina; Laboratory Corporation of America Holdings is mainly present into life sciences research that is deeply integrated in guiding patient care, providing comprehensive clinical laboratory, and end-to end drug development services. The company reported its business in two segments including LabCorp Diagnostics (LCD) and Covance Drug Development (CDD). LabCorp Diagnostics is an independent clinical laboratory business. The diagnostic segment has comprehensive portfolio of frequently requested and specialty testing through an integrated network of primary and specialty laboratories across the U.S. In addition, LCD also offers a range of other testing services, including forensic DNA analysis, food safety and integrity services, as well as occupational and wellness testing for employers.
The Covance Drug Development provides end-to-end drug development services from early-stage research to clinical trial management. The CDD is an Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) accredited provider of purpose-bred research models globally. Due to various regulations by the FDA and other foreign regulatory bodies, safety and efficacy testing on research models is required as part of the drug development process prior to testing in humans.CDD offers purpose-bred-specific, pathogen free rabbits, canines, nonhuman primates, and other species, as well as blood and tissue products and surgical/technical services, including telemetry. The purpose-bred research animals are sold to biopharmaceutical companies, university research centers, and CROs. Laboratory Corporation of America Holdings has its geographic presence in North America, Europe, and others.
Horizon Discovery Group plc
Founded in 2005 and headquartered at Cambridge, the United Kingdom; Horizon Discovery Group plc have various market segments such as cell and in vivo models, cell-based assay and screening, bioproduction, and molecular diagnostics. The company’s core capabilities are based on its translational genomics platforms, which include suits of genetic editing tools such as rAAV, ZFN, and CRISPR to alter gene sequence in human or mammalian cell-lines. The company offers approx. 23,000 cell lines, derived reagents, and in vivo models through direct sales, web-shop and ecommerce platform, and distribution partners. It also provides independent reference materials to routinely monitor the performance of workflows and assays, gene-editing, isogenic cell line assays, screening platforms, and invivo models to help solve research and drug development challenges. The company also provides products and services for the production of molecule therapeutics, offering solutions for organizations of various sizes; and genetically-defined isogenic cell lines and in-vivo research models.
The company supplies its products and services to academic research, drug discovery and manufacturing, and clinical diagnostics markets. The company has its geographic presence in North America, Europe, Asia-Pacific, and Middle East & Africa.
Trans Genic Inc.
Founded in 1998 and headquartered at Fukuoka, Japan; Trans Genic Inc. mainly develops, distributes, and licenses genetically engineered animals and antibodies. The company operates in genomics business, CRO business, advanced medical business, and pathological diagnostics business. The company engages in the custom production of genetically engineered mice, comprised of conventional, conditional, knockout and knocks in mice; and customized mouse-related analysis, such as speed congenics and phenotype analysis, including blood examination. In addition, the company provides mouse-related products, such as circadian locomotor output cycles kaput mice used as disease models; frozen embryos used to produce genetically engineered mice; and electronic instruction manual of reproduction technology for embryo manipulation, as well as approximately 600 antibody products.
The company also offers drug discovery support services such as clinical and non-clinical pharmacological tests Parkinson’s and Alzheimer’s diseases; and high density human tissue microarrays for use in the assessment of drug target molecules.
GenOway
Founded in 1999 and headquartered at Lyon, France; genOway mainly focuses on the development and sale of customized genetically modified mouse models across the globe. The company is also providing highly advanced technological solutions for transgenesis and model design, with the scientific consulting during the development. In addition, company offers GM animals, which includes custom mouse models, such as knockout and knockin models; custom rat models; custom cell models; catalog models; and phenotyping for in vivo or in vitro studies. The company also provides various patented technologies such as homologous recombination technology for the generation of humanized GM rodent models; CRISPR/Cas9 nuclease systems for the knockout and knockin model creation; and FLEx, an inducible point mutation technology for the development of mutated mice models.
The company has generated more than 1,500 genetically modified models in past 16 years while working with more than 80 pharmaceutical and biotech companies and 265 leading academic institutes. genOway utilizes its consultation services to better understand your specific research needs, objectives and goals as well as to help enhance the reliability of your in vivo and in vitro studies.
Taconic Biosciences, Inc.
Founded in 1949 and headquartered at Rensselaer, New York; Taconic Biosciences, Inc. provides custom research model generation and breeding integrated services for its customers. It offers conventional and genetically modified cryopreserved and live mice and rat for research, which helps in finding, designing, and breeding and preparing the researchers model. The company has comprehensive portfolio of precision research models, neuroscience model, and ADMET.
The company also provides various services, including cryopreservation, licensing, and molecular analysis by using various approaches. The company has its geographic presence in North America and Europe.
Envigo
Founded in 2015 and headquartered at Hackensack, New Jersey; Envigo provides essential products and services for pharmaceuticals development, crop protection, and chemical companies along with various universities, and government and other research organizations. In addition, the company’s research models and services provide research models, which include outbred, inbred, spontaneous mutant, and hybrid. This segment also produces and sells laboratory animal diets, bedding, and enrichment products under Teklad brand name; and offers research model services, including cannulation, implants, and the creation of surgically derived disease state models. The company also provides services, which includes surgical services, research model services, genetic testing services, European contract breeding services, and biological products and antibody production services.
In addition, the company provides contract breeding, contract colony management, health monitoring, quarantine, cryopreservation, and rederivation and revitalization services, as well as develops and produces antibody models. The company has its geographic presence in North America, Europe, Asia-Pacific, and Middle East region.
JANVIER LABS
Founded in 1960 and headquartered at Le Genest-Saint-Isle, France; JANVIER LABS mainly provides rodent research models and services across the globe. The company has four different segments, which includes research models, laboratory services, productive sciences, and customized breeding. The company has facility to provide research models with high stability, using cryopreservation and by renewing breeders regularly every 10 generations, and with a high level of health. The company provides various research models, which includes inbred mice, outbred mice, mutant mice, hybrid mice, and gerbils for research.
The company’s laboratory services comprised of surgery, various biological products, and experimental protocol. In addition, company also provides transgenic services to facilitate research.
Ingenious Targeting Laboratory (Ingenious)
Founded in 1998 and headquartered at Ronkonkoma, New York; Ingenious Targeting Laboratory (Ingenious) has broad portfolio of customized genetically modified mouse models. The advanced and versatile mouse model type includes conditional point mutants, and conditional knockout incorporating reporter genes, which supports research across the globe.
The company also has expertise in custom CRISPR rodent models with CRISPR knockout, point mutation, and small sequence insertion. The company also provides various vector creation, gene targeted ES cell lines and has its geographic presence in 44 countries across the globe.
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