ELISA Market Size, Share, Forecast, & Trends Analysis by Type (Direct, Sandwich, Competitive) Offering (Analyzer, Software) Technology (Chemiluminescence, Colorimetry, Fluorescence) Application (Research, Diagnostic) End User - Global Forecast to 2031

The ELISA Market was valued at $20.49 billion in 2023. This market is expected to reach $32.69 billion by 2031 from an estimated $21.63 billion in 2024, at a CAGR of 6.1% during the forecast period 2024-2031

ELISA Market Size & Forecast

The growth of the ELISA market is primarily driven by the high burden of chronic & infectious diseases, the increasing use of ELISA in clinical applications, advancements in ELISA, and the growing use of ELISA in the food industry. Furthermore, growing research activities in developing countries, increasing R&D for biomarker detection, and the growing focus on vaccine development are expected to offer growth opportunities for market stakeholders.

ELISA Market Growth Drivers

High Burden of Chronic & Infectious Diseases

ELISA is performed to detect or screen patients for diseases such as cancer, HIV, and autoimmune diseases. The rising prevalence of these diseases drives the utilization of ELISA kits. According to the World Health Organization (WHO) report published in July 2023, nearly 39 million people had HIV as of 2022.

ELISA uses antibodies that are specific and sensitive to target antigens. It can detect lower concentrations of biomarkers. In cancer detection, ELISA kits detect biomarkers such as Alpha-fetoprotein (AFP) and β-2microglobulin (B2M). ELISA is easier to perform and provides results faster compared to other tests. According to GLOBOCAN, the number of new cancer cases is expected to rise by 63.4% between 2022 and 2045. Thus, rising cancer incidence and the high preference for ELISA tests in cancer detection and diagnosis drive the growth of this market.

Click here to: Get Free Sample Pages of this Report

Advancements in ELISA

ELISA is used to detect and measure antigens in biological samples. In recent years, key players have been focused on advancing ELISA. The integration of nanomaterials in ELISA is one such advancement that has improved sensitivity, enhanced overall performance, and helped in the detection of trace amounts of proteins or biomarkers. Nanomaterials such as white Fe-based Coordination Polymer Nanozymes (FCPN), Multiwalled Carbon Nanotubes (MWCNTs), and Metallic Nanoparticles (NP) help in hassle-free enzyme loading.

Aptamers produced through chemical synthesis are now replacing antibodies in ELISA procedures. Aptamers can be modified as required and are cheaper to produce. Also, aptamers can be synthesized against a wide range of target molecules; hence, ELISA tests can be used for detecting many chronic & infectious diseases. These advancements have enabled more accurate and faster results, easy processing, and cost and time savings.

ELISA Market Trends

Digital ELISA

Digital ELISA is considered an advanced and sensitive immunoassay technique built on the principles of the traditional ELISA technique. Digital ELISA uses beads to induce enzyme reactions in femtoliter-sized wells that can detect single-enzyme molecules. The technique is used to accurately detect biomarkers or proteins in ultra-low-level concentration solutions. Magnetic microbead detection, single-molecule counting, and electrochemical detection are some of the types of digital ELISA. Digital ELISA helps researchers and scientists optimize results faster and more accurately. Digital ELISA serves applications in environmental monitoring, drug discovery, and clinical diagnostics. For instance, digital ELISA supports neurological research and diagnostics by measuring brain biomarkers. Digital ELISA offers high sensitivity, flexibility, and multiplexed capabilities. Quanterix Corp. (U.S.) offers digital ELISA for the detection of brain biomarkers.

Robotics & Automation

The integration of robotics and automation in ELISA streamlines the entire assay process, from sample preparation to data analysis. Automation helps in precise processing by dispensing accurate amounts of required reagents and samples. It helps in decreasing variabilities from the results and reducing the time required for conducting experiments. Automation and robotics improve accuracy and reproducibility as robots work on algorithms that do not change, reducing the risk of variations in sample volumes and detection time.

Automation and robotics follow system-integrated workflows that result in seamless processing without interruptions. ELISA robots can simultaneously perform pipetting procedures for multiple assays. Simultaneous processing results in reduced manual errors and increases time efficiency. According to Automata (U.K.), the use of ELISA robots reduces manual intervention during assays by 80%-95.25%.

ELISA Market Opportunities

Increasing R&D for Biomarker Detection

Biomarkers are biomolecules present in cells that help in disease detection. Biomarkers are largely used for identifying mutations and other chromosomal abnormalities during the detection of early-stage cancers. Biomarker detection helps in assessing diagnostic, predictive and monitoring results. Patients’ increasing inclination toward personalized medicines is increasing the utilization of ELISA for biomarker detection. In precision medicine, biomarker estimation helps in designing treatment strategies and optimizing therapeutic outcomes for patients. Thus, the growing focus on precision medicine coupled with high cancer prevalence is increasing research in the area of biomarker detection. Also, funding for biomarker R&D is increasing, generating opportunities for market growth. For instance, in August 2023, the National Comprehensive Cancer Network (U.S.), an alliance of 33 cancer centers in the U.S., in partnership with Fight Colorectal Cancer (U.S.), a patient empowerment organization, and Pfizer Inc. (U.S.), announced new grants for initiatives focused on optimizing biomarker-directed therapy for metastatic colorectal cancer.

ELISA Market Analysis: Key Findings

By Type: The Indirect ELISA Segment to Dominate the Market in 2024

Based on type, the ELISA market is segmented into direct ELISA, indirect ELISA, sandwich ELISA, and competitive ELISA. In 2024, the indirect ELISA segment is expected to account for the largest share of 43.5% of the ELISA market. Indirect ELISA is a detection type where a primary antigen-specific antibody is recognized by a secondary conjugated antibody. Indirect ELISA is highly sensitive and flexible, which helps in binding more than one labeled secondary antibody. Indirect ELISA uses fewer labeled antibodies and is used to detect total antibody concentrations in biological samples. Thus, the high sensitivity, flexibility, and cost-effectiveness of indirect ELISA contribute to the segment’s large market share.

By Offering: The Kits & Assays Segment to Dominate the ELISA Market in 2024

Based on offering, the ELISA market is segmented into kits & assays, analyzers, and software. In 2024, the kits & assays segment is expected to account for the largest share of 85.2% of the ELISA market. ELISA kits are commonly used for disease diagnosis, pregnancy testing, cancer detection, vaccine development, and food allergen testing. The rising prevalence of diseases, coupled with growing awareness regarding early disease diagnosis, is contributing to the segment’s large market share.

By Technology: The Colorimetric ELISA Segment to Dominate the Market in 2024

Based on technology, the ELISA market is segmented into chemiluminescence ELISA, colorimetric ELISA, and fluorescence ELISA. In 2024, the colorimetric ELISA segment is expected to account for the largest share of the ELISA market. Colorimetric ELISA uses colored reaction products to produce results. It uses labeled enzymes such as peroxidase or phosphatase for testing. Colorimetric ELISA is used for various types of samples, making it ideal for research applications. Colorimetric ELISA is non-destructive, and the samples can be used for further analysis. These factors support the segment’s large market share.

By Application: The Diagnostic Applications Segment to Dominate the ELISA Market in 2024

Based on application, the ELISA market is segmented into research applications, diagnostic applications, food testing, and other applications. In 2024, the diagnostic applications segment is expected to account for the largest share of the ELISA market. Diagnostic applications are further subsegmented into infectious diseases, autoimmune diseases, oncology, and other diagnostic applications. The increasing prevalence of cancer, autoimmune diseases, and infectious diseases is driving the utilization of ELISA kits in diagnostic applications.

 According to the National Institute of Environmental Health Sciences (NIEHS), 50 million people in the U.S. have autoimmune diseases. Thus, the high prevalence of target diseases, coupled with the benefits of ELISA, such as high sensitivity, accuracy, and reliability, supports the segment’s large share.

By End User: The Diagnostic Laboratories Segment to Dominate the ELISA Market in 2024

Based on end user, the ELISA market is segmented into pharmaceutical & biotechnology companies, diagnostic laboratories, CDMOs & CROs, academic & research institutes, food laboratories, and other end users. In 2024, the diagnostic laboratories segment is expected to account for the largest share of the ELISA market. The segment’s large share is attributed to the high prevalence of infectious and chronic diseases, the reliable test results provided by diagnostic laboratories, and the expansion of diagnostic laboratories. Diagnostic laboratories perform various medical tests that help identify and diagnose medical conditions. Diagnostic laboratories are well-equipped with advanced technological solutions and, therefore, are able to process more samples quicker. Thus, the rising burden of diseases and diagnostic laboratories’ high preference for ELISA tests contribute to the segment’s large share.

Geographic Analysis

North America to Dominate the ELISA Market in 2024

In 2024, North America is expected to account for the largest share of 37.7% of the ELISA market. The region’s large share is attributed to pharmaceutical companies’ high focus on R&D, supportive government initiatives, and the presence of large pharmaceutical players in the region. There is also an increased focus on food testing due to the increasing number of food adulteration cases in the region. Key players in North America are also undertaking strategic initiatives to increase food testing capacities in the region. For instance, in June 2024, Spectacular Labs Inc. (U.S.) collaborated with the Canadian Centre for Meat Innovation & Technology to improve food safety testing. Similarly, in June 2023, Bureau Veritas (France) opened its fourth food laboratory in the U.S. in Chesterfield, Missouri. The laboratory offers rapid and conventional microbiology testing for food and agricultural commodities. Such developments are expected to drive the demand for ELISA kits for food testing, supporting the growth of this regional market.

However, Asia-Pacific is slated to register the highest growth rate of 7.1% during the forecast period. The increasing number of healthcare facilities, diagnostic laboratories, and food testing laboratories in Asia-Pacific are driving the demand for ELISA in the region. Additionally, government initiatives for veterinary disease testing are driving the ELISA market in the region. Countries’ growing focus on improving human and animal healthcare, increasing investments in drug discovery, growth in diagnostic testing, and the growing focus on vaccination in Asia-Pacific are driving the demand for ELISA in the region. For instance, in May 2024, the Government of Australia started its vaccination drive for Influenza and released the list of available vaccines (Source: Commonwealth of Australia).

ELISA Market: Key Companies

The report includes a competitive landscape based on an extensive assessment of the product offerings, geographic presence, and key strategic developments of leading market players (2021–2024). The key players operating in the ELISA market include Thermo Fisher Scientific Inc. (U.S.), Merck KGaA (Germany), Bio-Rad Laboratories Inc. (U.S.), F. Hoffmann-La Roche AG (Switzerland), Danaher Corporation (U.S.), QIAGEN N.V. (Netherlands), Agilent Technologies, Inc. (U.S.), Abbott Laboratories (U.S.), bioMérieux SA (France), Revvity Inc. (U.S.), QuidelOrtho Corporation (U.S.), Becton, Dickinson and Company (U.S.), Repligen Corporation (U.S.), BioLegend (U.S.), and Bio-Techne Corporation (U.S.).

ELISA Market Overview: Latest Developments from Key Industry Players

• In February 2024, Gold Standard Diagnostics. (U.S.) launched Celer AFLA HS, an ELISA test kit for total aflatoxins detection in agricultural products such as maize and corn germ.
• In January 2024, Rockland Immunochemicals, Inc. (U.S.) launched the AccuSignal Nuclease ELISA Kit for the detection of Serratia marcescens endonuclease & turbonuclease used in the manufacturing of biological therapeutics, gene therapies, and vaccines, among others.
• In November 2023, F. Hoffmann-La Roche AG (Switzerland) launched the Elecsys HBeAg quant immunoassay to assess both the presence and quantity of hepatitis B antigen in biological samples.

ELISA Market Research Summary

Key questions answered in the ELISA market report: