Next Generation Sequencing (NGS) Market by Offering (Kits [Library Prep, QC, DNA Extraction], System) Type (Genome, Exome, Targeted) Application (Reproductive, Oncology, Infectious) Technology (SBS, Nanopore, Nanoball, SMRT Seq) ΓÇô Global Forecast to 2030

Development of Portable Sequencing Technologies is Creating Significant Opportunities for The Market Growth

The ability to sequence genes of any organism to make clinical and research conclusions has proved to be a game changer for public health. Taking this forward, portable handheld sequencing devices are making way for the future growth of this market by making sequencing cheaper, simpler, and faster without the need for big clinical laboratories. Real-time sequencing has enabled researchers and physicians to have sequencing data on the spot and act instantly. The portable nanopore-based sequencers are designed with the potential to sequence the entire genome in less than USD 1,000. The device passes the DNA sequence through a pore within a small protein called the nanopore that is embedded within a membrane. The DNA molecule then passes through the nanopore connecting the template and the ΓÇòcomplementary strand with the adaptor. The connection of the strands with the adaptor initiates an electric current, which is typically recorded and represented in the form of a graph.

Real-time sequencing is now slowly being adopted in disease characterization, food, and healthcare industry to detect contaminants, plant genome analysis in crop processing, and more. For instance, Boston-based biotech company Ginkgo Bioworks used a MinION nanopore sequencing device to detect the toxic contaminants in the culture and alerted the operators to remove toxic components, thus, saving the culture. Also, the scientists in Madagascar, for the first time, performed DNA sequencing in the country using portable technology to rapidly identify the bacteria responsible for tuberculosis (TB) and its drug resistance profile.

Also, recently portable sequencing devices were proven useful for the early detection of Ebola and Zika viruses. According to Cornell University (U.S.), portable sequencing offers various advantages over benchtop sequencers. Portable sequencers are inexpensive, mobile, handy, and designed to be easily operable in the field. Moreover, they use the biochemical principle, which enables real-time streaming of the raw signal as soon as the DNA molecules are sensed.

Among Offerings, in 2023, the Consumables Segment is Estimated to Account for the Largest Share of the Market

The global NGS market is segmented into consumables, NGS platforms/instruments, software, and services. In 2023, the consumables segment is expected to account for the largest share of the global NGS market. The large market share of this segment is attributed to recurring demand for consumables and the rising adoption of NGS technology for clinical and research purposes.

The Targeted Genome Sequencing Segment is Estimated to Account for the Largest Share of the Market

Based on sequencing type, the global NGS market is segmented into targeted genome sequencing, whole genome sequencing, whole exome sequencing, and other sequencing types. In 2023, the targeted genome sequencing segment is expected to account for the larger share of the global NGS market. The large market share of this segment is attributed to low sequencing costs compared to other sequencing technologies, higher sensitivity of the technique to call variants, and proven results in identifying primary immunodeficiencies and specific gene-associated diseases.

In 2023, the Sequencing by Synthesis Segment is Estimated to Account for the Largest Share of the Market

Based on technology, the global NGS market is segmented into sequencing by synthesis, ion semiconductor sequencing, single-molecule real-time sequencing (SMRT), nanopore sequencing, and DNA nanoball sequencing. In 2023, the sequencing by synthesis segment is expected to account for the largest share of the global NGS market. The key factors supporting the large market share of this segment are highly accurate output with base-by-base sequencing using sequencing by synthesis, reducing sequence-specific errors and enabling robust base calling across the entire genome, including repetitive sequences and homopolymers.

The Research and Other Applications Segment is Estimated to Account for the Largest Share of the Market

Based on application, the research and other applications segment is estimated to account for the largest share of the market. Increasing applications of NGS in research for oncology, agriculture and other research, rising advantages about the advantages of genetic research and testing using NGS technology, and increasing cancer cases are some of the factors expected to account for the largest share of research and other applications segment.

The Pharmaceutical & Biotechnology Companies Segment is Estimated to Account for the Largest Share of the NGS Market in 2023

The large share of this segment is primarily attributed to the increasing adoption of advanced technologies for research purposes, the availability of capital, and increasing research for drug discovery with widening NGS applications, thereby accounting for the largest share of the market.

The report offers a competitive landscape based on an extensive assessment of the product portfolio offerings, geographic presences, and key strategic developments adopted by leading market players in the industry over the years.The key players operating in the global NGS market are Illumina, Inc. (U.S.), Thermo Fisher Scientific Inc. (U.S.), F. Hoffmann-La Roche Ltd. (Switzerland), PerkinElmer, Inc. (U.S.), Qiagen N.V. (Netherlands), Agilent Technologies, Inc. (U.S.), Pacific Biosciences of California, Inc. (U.S.), Danaher Corporation (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Oxford Nanopore Technologies Plc. (U.K.), 10X Genomics, Inc. (U.S.), and Beijing Genomics Institute (BGI) (China).

Scope of the Report:

NGS Market Assessment, By Offering

• Consumables
  • Sample Preparation Consumables
    • DNA Extraction and Amplification
    • Library Preparation & Target Enrichment
    • Quality Control
  • Other Consumables
• NGS Platforms/Instruments
• Software
• Services
  (Other consumables include vials, pipettes, containers, trays, sequencing reagents, flow cells, and tubes)

NGS Market Assessment, by Sequencing Type

• Targeted Genome Sequencing
• Whole Genome Sequencing
• Whole Exome Sequencing
• Other Sequencing Types
  (Other sequencing types include degradome sequencing, chromatin immunoprecipitation (ChIP) sequencing, and methylation sequencing)

NGS Market Assessment, by Technology

• Sequencing by Synthesis
• Ion Semiconductor Sequencing
• Single-molecule Real-time Sequencing (SMRT)
• Nanopore Sequencing
• DNA nanoball sequencing

NGS Market Assessment, by Application

• Research Applications
• Drug Discovery
• Agriculture & Animal Research
• Other Research Applications
• Clinical Applications
• Reproductive Health Diagnosis
• Oncology
• Infectious Diseases
• Other Clinical Applications
  (Other research applications include food microbiology, microbiota analysis in the beverage industry, and environmental studies, and other clinical applications include the detection of genetic aberrations in neurological disorders, rare diseases, metabolic and immune disorders, and food-borne illnesses)

NGS Market Assessment, by End User

• Hospitals and Diagnostic Laboratories
• Pharmaceutical & Biotechnology Companies
• Academic Institutes & Research Centers
• Other End Users
  (Other end users include forensic laboratories & security agencies, food & beverage companies, and agriculture companies)

NGS Market Assessment, by Geography

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • U.K.
  • France
  • Italy
  • Spain
  • Rest of Europe (RoE)
• Asia-Pacific (APAC)
  • China
  • Japan
  • India
  • Rest of Asia-Pacific (RoAPAC)
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America (RoLATAM)
• Middle East & Africa

Key questions answered in the report

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