Neurogenomics is the study of how the gene contributes to the structure, function, and development of the nervous system. It involves investigations of how genome products (proteomes and transcriptomes) vary in space and time. Neurogenomics diverges significantly from the application of genetic sciences to other systems, mainly in the spatial category, due to connectivity and anatomy being principal to the understanding of nervous system functions.
Growing Need for the Early Detection & Prevention of Neurological Diseases
China accounts for approximately 17% of the global disease burden related to neurological, mental, and substance use disorders. The country is rapidly undergoing a societal change, facing challenges in reducing the disease burden of psychiatric disorders. For instance, China faces the greatest burden of stroke globally. According to results from the Global Burden of Disease Study 2019, there were 3.94 million new stroke cases, 28.76 million prevalent stroke cases, and 2.19 million deaths due to stroke in China in 2019 (Source: Data Management and Sharing System of the China National Clinical Research Center for Neurological Diseases). Furthermore, cases of Alzheimer’s disease are adding to the growing burden of neurological diseases in the country.
According to a recent national cross-sectional study, China had 15.07 million individuals aged 60 years and over with dementia, which includes 9.83 million individuals with Alzheimer’s disease, 3.92 million individuals with vascular dementia, and nearly 1.32 million individuals with other forms of dementia. Additionally, the prevalence of Mild Cognitive Impairment (MCI) in individuals over 60 years of age was 15.5%, with 38.77 million individuals affected by the condition (Source: The China Alzheimer Report 2022). Such a steady increase in the prevalence of neurological disorders is expected to boost the demand for advanced clinical and research solutions in the country.
Active Research in Genomics and Proteomics
During the last decade, active research in genomics and proteomics has increased, mainly due to technological advancements and the need to understand the genetic and molecular makeup of various neurological diseases. Traditionally, conventional technologies such as Sanger’s, which could sequence and analyze single genes, amplicon targets, genomic fragments, and short tandem repeats, were used in proteomics and genomics research. However, according to the National Human Genome Research Institute, Sanger sequencing can produce inaccurate results in many cases, provide low throughput, and be time-consuming. Hence, it has recently been replaced by Next-generation Sequencing (NGS), which can analyze 100 genes simultaneously, needs a low amount of input, and is significantly more cost-effective. Sanger sequencing costs about USD 500 per 1,000 bases, whereas NGS costs USD 0.50 per 1,000 bases. Moreover, the use of NGS in neurogenomics studies has enabled researchers to accurately identify disease genes, improve diagnosis, screen for gene mutations, and provide genetic counseling. Thus, active research in genomics and proteomics is increasing the demand for advanced clinical & research solutions to obtain more precise and fruitful insights for neurogenomics studies.
China Neurogenomics Market Analysis
Recent insights from Meticulous Research® provide valuable perspectives on the future trajectory of the neurogenomics industry in China. Projections suggest a potential worth of $562.1 million by 2031, driven by a remarkable Compound Annual Growth Rate (CAGR) of 19.4% from 2024 to 2031.
Notably, influential industry players, including Illumina, Inc. (U.S.), Thermo Fisher Scientific, Inc. (U.S.), MGI Tech Co., Ltd. (China), F. Hoffmann-La Roche Ltd. (Switzerland), and Revvity, Inc. (U.S.) and other major players have established a broad presence across various regions, leading to the widespread adoption of their consumables and instruments for diagnostic and research purposes.
Conclusion
The rising focus on genomics studies globally has propelled the demand for advanced neurogenomics solutions. Additionally, diagnoses of neurological diseases facilitated by advanced technologies are reshaping approaches toward the treatment of several neurological conditions, making them more effective and precise.
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